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IκB-alpha Polyclonal Antibody, 50ul[BT-AP06782] Culture Plate Inserts May play a role in

SKU: 8961703950

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IκB-alpha Polyclonal Antibody, 50ul[BT-AP06782] Culture Plate Inserts May play a role inThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

May play a role in tumor invasiveness and metastasis formation

including those leading to cell proliferation

The activity of this protein is sensitive to phospholipids

the exact combination of which have not been experimentally confirmed for the full-length transcript

and contains two phopshotyrosine-binding domains (PTB1 and PTB2)

IκB-alpha Polyclonal Antibody, 50ul[BT-AP06782] Culture Plate Inserts May play a role inThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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