HMG-1 Polyclonal Antibody, 50ul[BT-AP04141] Contamination Detection & Removal The protein encoded by this

The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane

Loss of function of EPN1 is associated with reduced tumor growth and progression in certain cancer types

Genetic variations of this gene have been associated with Parkinson disease susceptibility

Alternatively spliced transcript variants have been found for TECR

brain and liver

HMG-1 Polyclonal Antibody, 50ul[BT-AP04141] Contamination Detection & Removal The protein encoded by thisHMGB1 encodes high mobility group box 1 that belongs to the High Mobility Group box superfamily. The encoded non histone, nuclear DNA binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript