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STRUM Rabbit Polyclonal Antibody, 20ul Recombinant Protein Expression The protein is an E3

SKU: 87941115164

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STRUM Rabbit Polyclonal Antibody, 20ul Recombinant Protein Expression The protein is an E3This gene encodes a 134 kDa protein named strumpellin that is predicted to have multiple transmembrane domains and a spectrin repeat containing domain. This ubiquitously expressed gene has its highest expression in skeletal muscle. The protein is named for Strumpell disease; a form of hereditary spastic paraplegia (HSP). Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive lower

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Description

The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins

Some isoforms dominantly inhibit the activity of other estrogen receptor family members

Vesicle transport through interaction with t-SNAREs homolog 1A encoded by VTI1A is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking

MUC1 is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain

Although its endogenous substrate has not been determined

STRUM Rabbit Polyclonal Antibody, 20ul Recombinant Protein Expression The protein is an E3This gene encodes a 134 kDa protein named strumpellin that is predicted to have multiple transmembrane domains and a spectrin repeat containing domain. This ubiquitously expressed gene has its highest expression in skeletal muscle. The protein is named for Strumpell disease; a form of hereditary spastic paraplegia (HSP). Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive lower

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