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EGFR Polyclonal Antibody, 20ul[BT-AP15380] Erlenmeyer Flasks ANX4 is almost exclusively expressed

SKU: 87790324008

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EGFR Polyclonal Antibody, 20ul[BT-AP15380] Erlenmeyer Flasks ANX4 is almost exclusively expressedThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

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Description

ANX4 is almost exclusively expressed in epithelial cells

|subunit:When phosphorylated| interacts directly with the PIK3R1 subunit of phosphoinositide 3-kinase and the SH2 domains of GRB2| GRAP| GRAP2| PLCG1 and PLCG2

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This protein is one of four receptors identified for prostaglandin E2 (PGE2)

The capping activity of this protein is dependent on its association with tropomyosin

EGFR Polyclonal Antibody, 20ul[BT-AP15380] Erlenmeyer Flasks ANX4 is almost exclusively expressedThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

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