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FTO Polyclonal Antibody, 50ul Biomatrix MARCH8 induces the internalization of

SKU: 87361644009

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FTO Polyclonal Antibody, 50ul Biomatrix MARCH8 induces the internalization ofFTO is a nuclear protein of the AlkB related non haem iron and 2 oxoglutarate dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

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Description

MARCH8 induces the internalization of several membrane glycoproteins (Goto et al

This gene encodes an NADPH sensor protein that preferentially binds to NADPH

RPL5 (ribosomal protein L5) encodes a ribosomal protein that is a component of the 60S subunit

This gene encodes an epsilon subunit

The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein

FTO Polyclonal Antibody, 50ul Biomatrix MARCH8 induces the internalization ofFTO is a nuclear protein of the AlkB related non haem iron and 2 oxoglutarate dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

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