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Raf-1 Polyclonal Antibody, 50ul[BT-AP07628] ADME This gene encodes a protein

SKU: 86748776913

4.8
SEK162.00 SEK198.00

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Raf-1 Polyclonal Antibody, 50ul[BT-AP07628] ADME This gene encodes a proteinRAF1 (Raf 1 proto oncogene, serine threonine kinase) is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine

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Description

This gene encodes a protein that plays a role in pre-18s rRNA processing and small ribosomal subunit assembly

CASP8 and FADD-like apoptosis regulator encoded by CFLAR is a regulator of apoptosis and is structurally similar to caspase-8

This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1)

An alternative open reading frame product of this gene has been described in PMID:10399963

Polymorphisms in this gene| especially rs1344706| are thought to confer increased susceptibility to schizophrenia| bipolar disorder| and heroin addiciton

Raf-1 Polyclonal Antibody, 50ul[BT-AP07628] ADME This gene encodes a proteinRAF1 (Raf 1 proto oncogene, serine threonine kinase) is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine

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