FAF1 Polyclonal Antibody, 100ul[BT-AP03130] Gloves This enzyme plays a central

This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway

MIM 608818)| which is a member of the netrin family of axon guidance molecules (Lin et al

Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome| non-Hodgkin lymphoma and gastric cancer

Contains 2 C2 domains

It is not activated by phorbolesters or diacylglycerol

FAF1 Polyclonal Antibody, 100ul[BT-AP03130] Gloves This enzyme plays a centralInteraction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The Fas associated factor 1 encoded by FAF1 binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by FAF1 requires a ubiquitin like domain but not the FAS binding domain.