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P-Selectin Polyclonal Antibody, 100ul Buffers & Solutions Aberrant expression of this gene

SKU: 85262340647

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P-Selectin Polyclonal Antibody, 100ul Buffers & Solutions Aberrant expression of this geneSELP encodes a 140 kDa protein that is stored in the alpha granules of platelets and Weibel Palade bodies of endothelial cells. P selectin redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils

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Description

Aberrant expression of this gene is associated with cancer progression in multiple tissues

Alternatively spliced transcript variants have been found for

implying different ligand specificity

The Dbf4/Cdc7 protein kinase is essential for the activation of replication origins during S phase

Leukotrienes are important mediators of a number of inflammatory and allergic conditions

P-Selectin Polyclonal Antibody, 100ul Buffers & Solutions Aberrant expression of this geneSELP encodes a 140 kDa protein that is stored in the alpha granules of platelets and Weibel Palade bodies of endothelial cells. P selectin redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils

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