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Cdc16(Phospho Ser560) Polyclonal Antibody, 100ul Oligo Pool Mutations in NPM1 are associated

SKU: 84690845841

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Cdc16(Phospho Ser560) Polyclonal Antibody, 100ul Oligo Pool Mutations in NPM1 are associatedThe protein encoded by this gene functions as a protein ubiquitin ligase and is a component of the multiprotein APC complex. The APC complex is a cyclin degradation system that governs exit from mitosis by targeting cell cycle proteins for degredation by the 26S proteasome. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein, and other APC complex proteins, contain a tetratricopeptide repeat (TPR)

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Description

Mutations in NPM1 are associated with acute myeloid leukemia

this protein can undergo autophosphorylation

This protein translocates from caveolae to the cytoplasm after insulin stimulation

Diseases associated with MYF5 include skeletal muscle cancer and botryoid rhabdomyosarcoma

Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain

Cdc16(Phospho Ser560) Polyclonal Antibody, 100ul Oligo Pool Mutations in NPM1 are associatedThe protein encoded by this gene functions as a protein ubiquitin ligase and is a component of the multiprotein APC complex. The APC complex is a cyclin degradation system that governs exit from mitosis by targeting cell cycle proteins for degredation by the 26S proteasome. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein, and other APC complex proteins, contain a tetratricopeptide repeat (TPR)

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