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TRF1(Phospho Ser219) Polyclonal Antibody, 20ul Gene Editing Alternative splicing of this gene

SKU: 84502679206

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TRF1(Phospho Ser219) Polyclonal Antibody, 20ul Gene Editing Alternative splicing of this geneThis gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C terminal Myb motif, a dimerization domain near its N terminus and an acidic N terminus. Two transcripts of this gene are alternatively

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Description

Alternative splicing of this gene results in three transcript variants encoding distinct isoforms

and for interaction with anti-apoptotic members of the BCL2 family

Src family tyrosine kinase contains N-terminal sites for myristylation and palmitylation

The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins

Because of its pro-apoptotic role

TRF1(Phospho Ser219) Polyclonal Antibody, 20ul Gene Editing Alternative splicing of this geneThis gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C terminal Myb motif, a dimerization domain near its N terminus and an acidic N terminus. Two transcripts of this gene are alternatively

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