SYN2 Polyclonal Antibody, 20ul Proteases During mitosis it is associated

During mitosis it is associated with chromosomes

hypophosphorylated form of the protein binds transcription factor E2F1

A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17

but lacks several residues that are critical for catalytic activity

It is very conserved in evolution

SYN2 Polyclonal Antibody, 20ul Proteases During mitosis it is associatedThis gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron specific phosphoprotein