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ST5 Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) Gap-filling polymerase involved in repair

SKU: 83886434942

4.8
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ST5 Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) Gap-filling polymerase involved in repairST5 was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. Suppression of tumorigenicity 5 protein encoded by ST5 contains a C terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c Abl kinase, and acts as a regulator of MAPK1 ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three

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Description

Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ)

GO annotations related to this gene include protein kinase binding and phosphoprotein binding

and seven LRRs (aa 739-988)

The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis

proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport

ST5 Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) Gap-filling polymerase involved in repairST5 was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. Suppression of tumorigenicity 5 protein encoded by ST5 contains a C terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c Abl kinase, and acts as a regulator of MAPK1 ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three

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