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Integrin alphaD Polyclonal Antibody, 100ul Measuring Instruments RGR may be associated with

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Integrin alphaD Polyclonal Antibody, 100ul Measuring Instruments RGR may be associated withThis gene belongs to the beta 2 integrin family of membrane glycoproteins, which are are composed of non covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue

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Description

RGR may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP

The transcript contains multiple polyadenylation and mRNA instability signals

Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546| 20937277)

Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage

5 mL is RCF 30

Integrin alphaD Polyclonal Antibody, 100ul Measuring Instruments RGR may be associated withThis gene belongs to the beta 2 integrin family of membrane glycoproteins, which are are composed of non covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue

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