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RPGF6 Polyclonal Antibody, 100ul Cell fragmentation and collection |tissue specificity:Expressed in hematopoietic cells

SKU: 83726090213

4.2
SEK141.00 SEK173.00

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RPGF6 Polyclonal Antibody, 100ul Cell fragmentation and collection |tissue specificity:Expressed in hematopoietic cellsGuanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M Ras GTPases. Does not interact with cAMP.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,Contains 1 cyclic nucleotide binding domain.,Contains 1 N terminal Ras GEF domain.,Contains 1 PDZ (DHR) domain.,Contains 1 Ras associating domain.,Contains 1 Ras GEF domain.,subcellular location: Upon binding to M Ras, it translocates to the plasma membrane.,subunit: Interacts with the

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Description

|tissue specificity:Expressed in hematopoietic cells and also in colon and testis

Mutations in RAB3GAP2 are associated with Martsolf syndrome

The encoded protein catalyzes the dephosphorylation of phosphotyrosine and phosphatidylinositol and plays roles in cellular proliferation and differentiation

May play a role in all aspects of hemoglobin production: globin synthesis| heme synthesis| and the procurement of iron

Mutations in this gene are associated with septooptic dysplasia

RPGF6 Polyclonal Antibody, 100ul Cell fragmentation and collection |tissue specificity:Expressed in hematopoietic cellsGuanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M Ras GTPases. Does not interact with cAMP.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,Contains 1 cyclic nucleotide binding domain.,Contains 1 N terminal Ras GEF domain.,Contains 1 PDZ (DHR) domain.,Contains 1 Ras associating domain.,Contains 1 Ras GEF domain.,subcellular location: Upon binding to M Ras, it translocates to the plasma membrane.,subunit: Interacts with the

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