MED11 Polyclonal Antibody, 100ul Buffers & Solutions Mutations in this gene may

Mutations in this gene may be associated with congenital aural atresia syndrome

cyclin L1 can be overexpressed and is therefore often considered a proto-oncogene

The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs

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including both secreted and membrane associated proteins

MED11 Polyclonal Antibody, 100ul Buffers & Solutions Mutations in this gene mayMED11 is a component of the Mediator complex, which is a coactivator for DNA binding factors that activate transcription via RNA polymerase II (Sato et al., 2003