VNN2 Polyclonal Antibody, 50ul Apoptosis & Autophagy COQ8B encodes a protein with

COQ8B encodes a protein with two copies of a domain found in protein kinases

Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect

Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms

the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult

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VNN2 Polyclonal Antibody, 50ul Apoptosis & Autophagy COQ8B encodes a protein withThis gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative