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DB134 Rabbit Polyclonal Antibody, 20ul Digital Burette Activated by icilin

SKU: 83476787796

4.1
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DB134 Rabbit Polyclonal Antibody, 20ul Digital Burette Activated by icilinDefensins are cysteine rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The antimicrobial protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome with this gene mapping to a cluster at 8p23.

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Description

Activated by icilin

Proteins in this family are part of the ESCRT-III (endosomal sorting complex required for transport III) which degrades surface receptors

homologous to the HMG box of sex-determining region Y (SRY)

The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis| for instance| induced by G-protein-coupled-receptor signaling

TMEM113 (WDR82) is a component of the mammalian SET1A (MIM 611052)/SET1B (MIM 611055) histone H3-Lys4 methyltransferase complexes (Lee and Skalnik| 2005

DB134 Rabbit Polyclonal Antibody, 20ul Digital Burette Activated by icilinDefensins are cysteine rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The antimicrobial protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome with this gene mapping to a cluster at 8p23.

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