BRCA2 Polyclonal Antibody, 50ul Petri Dishes CYP24A1 encodes a member of

CYP24A1 encodes a member of the cytochrome P450 superfamily of enzymes

It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway

The protein functions as a guanine nucleotide exchange for RAB5B and RAB31

The protein encoded by this gene is a member of the dual specificity protein kinase family

including RNA polymerase II transcription

BRCA2 Polyclonal Antibody, 50ul Petri Dishes CYP24A1 encodes a member ofInherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is