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NCoA-5 Polyclonal Antibody, 20ul Molecular Biology a minor fibrillar collagen

SKU: 82891289634

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NCoA-5 Polyclonal Antibody, 20ul Molecular Biology a minor fibrillar collagenNCOA5 (nuclear receptor coactivator 5) encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Two alternatively spliced transcript variants for this

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Description

a minor fibrillar collagen

which can dimerize to form the double chain form of the enzyme

4-dienoyl-CoAs to 3-enoyl-CoAs

19-docosaheptaenoyl-CoA

A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes

NCoA-5 Polyclonal Antibody, 20ul Molecular Biology a minor fibrillar collagenNCOA5 (nuclear receptor coactivator 5) encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Two alternatively spliced transcript variants for this

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