Ku-70 Polyclonal Antibody, 100ul[BT-AP04895] Cell Proliferation Alternative splicing in the 5'

Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein

It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction

and shows structural similarity to p53-binding protein MDM2

Mutations in the gene encoding ataxin 3 are associated with Machado-Joseph disease

RBAK encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1

Ku-70 Polyclonal Antibody, 100ul[BT-AP04895] Cell Proliferation Alternative splicing in the 5'The p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with