CAPS2 Polyclonal Antibody, 100ul Drug Development and Evaluation Mutations in SLC4A11 have been

Mutations in SLC4A11 have been associated with a number of endothelial corneal dystrophies including recessive corneal endothelial dystrophy 2

transcriptional activation and cell cycle progression

This gene encodes an endoplasmic reticulum membrane protein that is required for utilization of the mannose donor mannose-P-dolichol in the synthesis of lipid-linked oligosaccharides and glycosylphosphatidylinositols

The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes

The encoded protease is constitutively secreted into the extracellular matrix and expressed in many tissues| including neuroendocrine| liver| gut| and brain

CAPS2 Polyclonal Antibody, 100ul Drug Development and Evaluation Mutations in SLC4A11 have beenThis gene encodes a member of the calcium dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense core vesicles in neurons and neuroendocrine cells. Mutations in this gene may contribute to autism susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene.