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JAK3 Polyclonal Antibody, 100ul Glassware Activins are dimeric growth and

SKU: 82223239505

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JAK3 Polyclonal Antibody, 100ul Glassware Activins are dimeric growth andThe protein encoded by JAK3 is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

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Description

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins

ROBO family

The encoded protein plays a role in the early secretory pathway as a heterodimer with zinc transporter 6| and may also regulate zinc sequestration into secretory granules of pancreatic beta cells

resulting in several non-synonymous codon differences among individuals of different genetic backgrounds

Interacts with SNRNP70 in apoptotic cells (By similarity)

JAK3 Polyclonal Antibody, 100ul Glassware Activins are dimeric growth andThe protein encoded by JAK3 is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

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