Stat5a Polyclonal Antibody, 20ul[BT-AP08639] Peptide Modification thought to be related to

thought to be related to the cytochrome c-mediated cell death pathway

The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form

which interacts with the sliding DNA clamp protein PCNA

RAD17 checkpoint clamp loader component recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage

Eukaryotic release factor 3 (eRF3) has many functions in eukaryotic cells

Stat5a Polyclonal Antibody, 20ul[BT-AP08639] Peptide Modification thought to be related toStat5 is activated in response to a wide variety of ligands including IL 2, GM CSF, growth hormone and prolactin. Phosphorylation at Tyr694 is obligatory for Stat5 activation. This phosphorylation is mediated by Src upon erythropoietin stimulation. Stat5 is constitutively active in some leukemic cell types. Phosphorylated Stat5 is found in some endothelial cells treated with IL 3, which suggests its involvement in angiogenesis and cell motility.