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Rb(Phospho Thr821) Polyclonal Antibody, 50ul Bottles This nuclear enzyme is involved

SKU: 81537480599

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Rb(Phospho Thr821) Polyclonal Antibody, 50ul Bottles This nuclear enzyme is involvedThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

This nuclear enzyme is involved in processes such as chromosome condensation

This protein binds both the calcium uptake pump SERCA2B and the carbohydrate-binding chaperone calnexin| and it appears to play a role in calcium homeostasis in the ER

a variant H2A histone that is enriched on inactivated X chromosomes

Belongs to the TFB2 family

hyperglycemia

Rb(Phospho Thr821) Polyclonal Antibody, 50ul Bottles This nuclear enzyme is involvedThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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