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PTP22 Polyclonal Antibody, 100ul Enzymes & Activity Assays APOBEC3F is a member of

SKU: 81191744384

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PTP22 Polyclonal Antibody, 100ul Enzymes & Activity Assays APOBEC3F is a member ofPTPN22 encodes of member of the non receptor class 4 subfamily of the protein tyrosine phosphatase family. The protein tyrosine phosphatase, non receptor type 22 is a lymphoid specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1

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Description

APOBEC3F is a member of the cytidine deaminase gene family

17-alpha-hydroxylase/17

1| where most DUF1220 domains are located| have been implicated in a number of developmental and neurogenetic diseases such as microcephaly| macrocephaly| autism| schizophrenia| mental retardation| congenital heart disease| neuroblastoma| and congenital kidney and urinary tract anomalies

The gene encoding TUSC5 maps to human chromosome 17

Participates in Wnt signaling

PTP22 Polyclonal Antibody, 100ul Enzymes & Activity Assays APOBEC3F is a member ofPTPN22 encodes of member of the non receptor class 4 subfamily of the protein tyrosine phosphatase family. The protein tyrosine phosphatase, non receptor type 22 is a lymphoid specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1

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