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HNF-1Beta Polyclonal Antibody, 100ul Centrifuges GATA1 encodes Erythroid transcription factor

SKU: 80981091824

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HNF-1Beta Polyclonal Antibody, 100ul Centrifuges GATA1 encodes Erythroid transcription factorHNF1B encodes a member of the homeodomain containing superfamily of transcription factors. Hepatocyte nuclear factor 1 beta binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1 alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin dependent diabetes

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Description

GATA1 encodes Erythroid transcription factor which belongs to the GATA family of transcription factors

This gene undergoes extensive alternative splicing to generate multiple isoforms| but the full-length nature of some of these variants has not been determined

Seems to negatively regulate apoptosis by promoting FADD phosphorylation

UBB consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence

hypomethylation of the CAGE promoter region is associated with tumor progression and may serve as a valuable marker in cancer diagnosis

HNF-1Beta Polyclonal Antibody, 100ul Centrifuges GATA1 encodes Erythroid transcription factorHNF1B encodes a member of the homeodomain containing superfamily of transcription factors. Hepatocyte nuclear factor 1 beta binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1 alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin dependent diabetes

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