Plk1 Polyclonal Antibody, 50ul Vortex Mixer The protein encoded by this

The protein encoded by this gene belongs the PI3/PI4-kinase family| and is most closely related to ATM| a protein kinase encoded by the gene mutated in ataxia telangiectasia

as well as in stabilization of I-kappa-B-alpha (NFKBIA

The LUC7L gene may represent a mammalian heterochromatic gene| encoding a putative RNA-binding protein similar to the yeast Luc7p subunit of the U1 snRNP splicing complex that is normally required for 5-prime splice site selection (Tufarelli et al

It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation

polymorphism: there seems to be a deletion in the gene coding for this protein in about 98% of the population

Plk1 Polyclonal Antibody, 50ul Vortex Mixer The protein encoded by thisSerine threonine protein kinase PLK1 kinase encoded by PLK1 belongs to the CDC5 Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy.