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XPA Polyclonal Antibody, 20ul Nucleic Acid Amplification Potassium-transporting ATPase alpha chain 2

SKU: 79015377071

4.3
USD97.20 USD145.20

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XPA Polyclonal Antibody, 20ul Nucleic Acid Amplification Potassium-transporting ATPase alpha chain 2XPA encodes a zinc finger protein involved in DNA excision repair. The DNA repair protein complementing XP A cells is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.

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Description

Potassium-transporting ATPase alpha chain 2 encoded by ATP12A belongs to the family of P-type cation transport ATPases

which function in protein-protein interactions

APOL2 is a member of the apolipoprotein L gene family

Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD (P)H-dependent oxido-reduction of carbonyl groups)

A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma

XPA Polyclonal Antibody, 20ul Nucleic Acid Amplification Potassium-transporting ATPase alpha chain 2XPA encodes a zinc finger protein involved in DNA excision repair. The DNA repair protein complementing XP A cells is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.

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