CD58 Polyclonal Antibody, 100ul[BT-AP02406] Cell Transfection The DNA binding and transcriptional

The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium

This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters

In this form| it circulates in the plasma| prolonging the half-life of IGFs and altering their interaction with cell surface receptors

Mutations in this gene may result in Netherton syndrome

The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs)

CD58 Polyclonal Antibody, 100ul[BT-AP02406] Cell Transfection The DNA binding and transcriptionalCYP2D6 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 25% of commonly prescribed drugs. Its substrates include antidepressants, antipsychotics, analgesics and antitussives, beta