Presenilin 2(Phospho Ser330) Polyclonal Antibody, 100ul Protein Post-translational Modification Two alternatively spliced transcript variants

Two alternatively spliced transcript variants have been described for this gene

This gene encodes a mitochondrial protein that interacts with reticulon 4| which is a potent inhibitor of regeneration following spinal cord injury

Transcription factor E2F4 encoded by E2F4 is a member of the E2F family of transcription factors

Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function

bone resorption

Presenilin 2(Phospho Ser330) Polyclonal Antibody, 100ul Protein Post-translational Modification Two alternatively spliced transcript variantsAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP. Also,