FGF-BP2 Polyclonal Antibody, 50ul Lysosome Mutations in this gene and

Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter

This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins

The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest| and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells

In a conventional activation pathway| I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators| subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus

It is a mediator of mitochondrial damage induced by caspase-8 (CASP8)

FGF-BP2 Polyclonal Antibody, 50ul Lysosome Mutations in this gene andFGFBP2 (fibroblast growth factor binding protein 2) encodes a member of the fibroblast growth factor binding protein family. The encoded protein is a serum protein that is selectively secreted by cytotoxic lymphocytes and may be involved in cytotoxic lymphocyte mediated immunity. An increase in the amount of gene product may be associated with atopic asthma and mild extrinsic asthma.