MYPT1 Polyclonal Antibody, 100ul[BT-AP05740] Apoptosis & Autophagy Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants encoding different isoforms have been reported

Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation

The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein| and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway

Mutations in CDKN1C are implicated in sporadic cancers and Beckwith-Wiedemann syndorome

SNAPC5 encodes a subunit of the small nuclear RNA (snRNA)-activating protein complex that plays a role in the transcription of snRNA genes

MYPT1 Polyclonal Antibody, 100ul[BT-AP05740] Apoptosis & Autophagy Multiple alternatively spliced transcript variantsMyosin phosphatase target subunit 1, which is also called the myosin binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in