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Rho H Polyclonal Antibody, 50ul Pipette Controller It may be a critical

SKU: 78276871027

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Rho H Polyclonal Antibody, 50ul Pipette Controller It may be a criticalThe protein encoded by RHOH is a member of the Ras superfamily of guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. RHOH may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non Hodgkin's lymphoma occur between this locus and B cell CLL lymphoma 6 (BCL6) on chromosome 3, leading to

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Description

It may be a critical substrate for p210 (bcr/abl)

The protein binds to specific DNA sequences

is a 287 amino acid secreted protein that contains one C1q domain and one collagen-like domain

It is widely distributed in peripheral organs| such as liver and kidney| and is also present in low amounts in the central nervous system

MALT1 and this protein are thought to synergize in the activation of NF-kappaB

Rho H Polyclonal Antibody, 50ul Pipette Controller It may be a criticalThe protein encoded by RHOH is a member of the Ras superfamily of guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. RHOH may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non Hodgkin's lymphoma occur between this locus and B cell CLL lymphoma 6 (BCL6) on chromosome 3, leading to

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