Tak1(Phospho Ser439) Polyclonal Antibody, 100ul Electrophoresis & Labeling Mutations in this gene underlie

Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome| Donohue syndrome and Rabson-Mendenhall syndrome

Interacts with HDAC3

There are two ACC forms

This protein may also be a potential biomarker for certain tumors

Mutations in this gene are associated with ocular coloboma

Tak1(Phospho Ser439) Polyclonal Antibody, 100ul Electrophoresis & Labeling Mutations in this gene underlieThe protein encoded by this gene is a member of the serine threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL 1, this protein forms a kinase complex including TRAF6, MAP3K7P1 TAB1 and MAP3K7P2 TAB2; this complex is required for the activation of nuclear factor