IP3R-I Polyclonal Antibody, 100ul[BT-AP04603] Dry Bath Expressed predominantly in the brain

Expressed predominantly in the brain

NBPF5 (neuroblastoma breakpoint family member 5) is a 351 amino acid cytoplasmic protein that is expressed in medulla and brain and belongs to the NBPF family

found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013)

including those involved in energy metabolism

The encoded protein also is required for the localization of some specific channels and can be part of a protein complex that couples synaptic vesicle exocytosis to cell adhesion in the brain

IP3R-I Polyclonal Antibody, 100ul[BT-AP04603] Dry Bath Expressed predominantly in the brainITPR1 (inositol 1,4,5 trisphosphate receptor type 1) encodes an intracellular receptor for inositol 1,4,5 trisphosphate. Upon stimulation by inositol 1,4,5 trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in ITPR1 cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for ITPR1.