ACADV Polyclonal Antibody, 100ul Pipette Controller RPL11 (ribosomal protein L11) encodes

RPL11 (ribosomal protein L11) encodes a ribosomal protein that is a component of the 60S subunit

Two alternatively spliced transcript variants encoding the same protein have been described for this gene

This protein is a member of the ALD subfamily| which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle

To date| all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size| sequence and predicted structure| but differ significantly in their tissue distributions

A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B

ACADV Polyclonal Antibody, 100ul Pipette Controller RPL11 (ribosomal protein L11) encodesThe protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta oxidation pathway. This acyl Coenzyme A dehydrogenase is specific to long chain and very long chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding