PLXB1 Polyclonal Antibody, 20ul Metabolic enzymes tool compounds Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants of this gene have been reported

A transcribed pseudogene of this gene has been identified on chromosome 15

This gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate

Read-through transcription also exists between CTNND1 and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene

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PLXB1 Polyclonal Antibody, 20ul Metabolic enzymes tool compounds Multiple alternatively spliced transcript variantsdisease: Overexpressed and constitutively tyrosine phosphorylated in colon, liver, pancreas and gastric carcinoma cell lines. Overexpression increases MET activation and promotes invasive growth.,Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,PTM: Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding.,PTM: