Histone H3 (Acetyl Lys9) Polyclonal Antibody, 20ul[BT-AP04046] Bio-Reaction Tube Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants encoding different isoforms have been found for CAPN9

Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue

An important paralog of this gene is RASGEF1A

and it is abrogated by mutations in the pleckstrin homology domain of AKT1

CASP3 encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family

Histone H3 (Acetyl Lys9) Polyclonal Antibody, 20ul[BT-AP04046] Bio-Reaction Tube Multiple alternatively spliced transcript variantsHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin