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TLX1 Polyclonal Antibody, 100ul Centrifuges Mutations of this gene have

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TLX1 Polyclonal Antibody, 100ul Centrifuges Mutations of this gene haveThis gene encodes a nuclear transcription factor that belongs to the NK linked or NK like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T cell acute lymphoblastic leukemias. Alternate splicing results in

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Description

Mutations of this gene have been reported to be associated with hereditary pheochromocytoma

Cofactors B and E can form a heterodimer which binds to alpha-tubulin and enhances their ability to dissociate tubulin heterodimers

the centripetal movement of lysosomes and endosomes

Three transcript variants encoding different isoforms have been found for CBF2alpha

Mutations in this gene have been associated with Oguchi disease

TLX1 Polyclonal Antibody, 100ul Centrifuges Mutations of this gene haveThis gene encodes a nuclear transcription factor that belongs to the NK linked or NK like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T cell acute lymphoblastic leukemias. Alternate splicing results in

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