HXC12 Polyclonal Antibody, 100ul Hybridoma Antibody Sequencing protein tyrosine kinase 2 beta

protein tyrosine kinase 2 beta undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration

Down-regulated in immortalized fibroblasts isolated after a proliferative crisis accompanied with massive cell death

The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members

which functions downstream of the Ras family of membrane associated GTPases to which it binds directly

This gene encodes a member of the PDE protein superfamily

HXC12 Polyclonal Antibody, 100ul Hybridoma Antibody Sequencing protein tyrosine kinase 2 betaThis gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on