REP-2 Polyclonal Antibody, 100ul Cell Labeling & Imaging Radial spokes| which are regularly

Radial spokes| which are regularly spaced along cilia| sperm| and flagella axonemes| consist of a thin 'stalk' and a bulbous 'head' that form a signal transduction scaffold between the central pair of microtubules and dynein

This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol

A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration

The Drosophila segment polarity gene lin encodes a protein| lines| which plays important roles in development of the epidermis and hindgut

and each has been shown to have human homolog(s)

REP-2 Polyclonal Antibody, 100ul Cell Labeling & Imaging Radial spokes| which are regularlyThe product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP 1 in tissues other than retina. CHML is localized close to the gene for Usher syndrome type II.