CD179b Polyclonal Antibody, 100ul Immunoassays Defects in PEX5 are a

Defects in PEX5 are a cause of neonatal adrenoleukodystrophy (NALD)

Contains 1 thyroglobulin type-1 domain

and downstream products

The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN

and all three proteins are similarly expressed in fibroblast cells such as NIH/3T3

CD179b Polyclonal Antibody, 100ul Immunoassays Defects in PEX5 are aThe preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene