CTNL1 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) CIB3 product shares a high

CIB3 product shares a high degree of sequence similarity with DNA-dependent protein kinase catalytic subunit-interacting protein 2 in human and mouse

The protein encoded by this gene contains an ankyrin repeat sequence and SOCS box domain

Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2

MIM 180690) (Baillat et al

Alternative splicing results in a multitude of transcript variants

CTNL1 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) CIB3 product shares a highMay modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).,induction: Down regulated in cancer pancreatic cells undergoing differentiation and apoptosis.,Belongs to the vinculin alpha catenin family.,subunit: Interacts with ARHGEF1.,tissue specificity: Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.,