GDF8 Polyclonal Antibody, 100ul ADME The protein may form a

The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains

These family members are transcription factors that are implicated in a variety of cellular processes

CCDC45 (coiled-coil domain containing 45) is a 821 amino acid protein encoded by a gene that maps to human chromosome 17q23

400 genes and comprises nearly 4% of the human genome

head and neck cancers

GDF8 Polyclonal Antibody, 100ul ADME The protein may form aThis gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. This protein negatively regulates skeletal muscle cell proliferation