CD141 Polyclonal Antibody, 50ul Nucleic Acid Isolation & Purification This protein localizes to focal

This protein localizes to focal adhesion sites and along actin stress fibers

|PTM:Phosphorylation at Ser-554 by PKB is required for interaction with ITGB1| export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration

The La motif is also found in proteins unrelated to the La protein

The T-box family members share a common DNA binding domain

Mutations in MYOZ2 cause cardiomyopathy familial hypertrophic type 16

CD141 Polyclonal Antibody, 50ul Nucleic Acid Isolation & Purification This protein localizes to focalThe protein encoded by this intronless gene THBD (thrombomodulin) is an endothelial specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in THBD are a cause of thromboembolic disease, also known as inherited thrombophilia.