NEK2 Polyclonal Antibody, 50ul Metabolic enzymes tool compounds Calreticulin is a multifunctional protein

Calreticulin is a multifunctional protein that acts as a major Ca (2+)-binding (storage) protein in the lumen of the endoplasmic reticulum

has been found to be required for IKK activation by this protein

allowing microhomologous sequences in the overhangs to form base pairs

Binds to GC boxes promoters elements

The encoded protein may play a role in breast cancer proliferation and chemoresistance

NEK2 Polyclonal Antibody, 50ul Metabolic enzymes tool compounds Calreticulin is a multifunctional proteinThis gene encodes a serine threonine protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C termini have been noted for this gene.