CPI-17(Phospho Thr38) Polyclonal Antibody, 100ul Peptide Synthesis 4 Mb region that is

4 Mb region that is commonly deleted in diverse tumors

Made from GPPS material

Methylation of the CpG island leads to transcriptional silencing of this gene

Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon

The LIM/double zinc-finger motif found in this gene product occurs in proteins with critical functions in gene regulation

CPI-17(Phospho Thr38) Polyclonal Antibody, 100ul Peptide Synthesis 4 Mb region that isThe protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.