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Chk1(Phospho Ser286) Polyclonal Antibody, 100ul Inoculating Loops/Needles It undergoes tyrosine phosphorylation and

SKU: 73511745175

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Chk1(Phospho Ser286) Polyclonal Antibody, 100ul Inoculating Loops/Needles It undergoes tyrosine phosphorylation andThe protein encoded by this gene belongs to the Ser Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells

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Description

It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs)

Sulfatases

The Smad proteins are subject to complex regulation by post-translational modifications

This gene has been found to be involved in translocations that result in fusions with other genes in various cancers

q34) with BRD3 which produces a BRD3-NUT fusion protein

Chk1(Phospho Ser286) Polyclonal Antibody, 100ul Inoculating Loops/Needles It undergoes tyrosine phosphorylation andThe protein encoded by this gene belongs to the Ser Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells

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