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The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon

Positively regulates the beta-catenin pathway (canonical Wnt signaling pathway) and is required for MCC-mediated repression of the beta-catenin pathway (PubMed: 24824780)

PP2CEpsilon Polyclonal Antibody, 20ul Mammalian Expression Take risks with our 2000Protein phosphatase 1L encoded by PPM1L is a magnesium or manganese requiring phosphatase that is involved in several signaling pathways. The encoded protein downregulates apoptosis signal regulating kinase 1, a protein that initiates a signaling cascade that leads to apoptosis when cells are subjected to cytotoxic stresses. This protein also is an endoplasmic reticulum transmembrane protein that helps regulate ceramide transport from the endoplasmic