HDAC3 Polyclonal Antibody, 50ul General Lab Use The alpha-3 subunit lacks the

The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits

and can filter samples up to 3

This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB

where it constitutes the regulatory subunit

Alternative splicing results in transcript variants encoding distinct isoforms

HDAC3 Polyclonal Antibody, 50ul General Lab Use The alpha-3 subunit lacks theHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 3 encoded by HDAC3 belongs to the histone deacetylase acuc apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of